
Added MD Protection with Addition of Serotype 2 Mareks Virus

Ultifend® is a HVT (Serotype 3) vector vaccine genetically engineered to expresses the VP2 gene of the Infectious Bursal Disease virus (IBDV) and the F gene of the Newcastle Disease virus (NDV).
ULTIFEND® IBD ND was selected from among 40 different vaccine candidates as the best construct for optimal protection against IBD, ND and Marek’s disease. Construct 3 was chosen because it demonstrated ND protection comparable to VECTORMUNE® ND and IBD protection comparable to the rHVT/VP2 STC construct.
ULTIFEND® IBD ND + RISPENS is a combination of the HVT vector vaccine expressing IBD and ND vaccine antigens with the conventional live Rispens (Serotype 1) Marek’s Disease vaccine, providing enhanced MD protection.
IBD Protection
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ND Protection
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IBD Protection
ULTIFEND® IBD ND at minimum protective dose achieved the 9 CFR requirement of at least 90% protection from standard IBD lesions.
Eighteen days old embryos were vaccinated via in ovo or day of age chickens were vaccinated via subcutaneous and challenged at 5 weeks of age with IBDV-STC challenge strain via eye-drop, according to 9 CFR. Necropsy to score for bursa lesions were performed to evaluate the percent protection of the vaccinates in comparison to non-placebo-vaccinated chickens (Study on file with CVB).
ND Protection
ULTIFEND® IBD ND at minimum protective dose achieved the 9 CFR requirement of at least 90% protection from mortality induced by ND virus infection.
Eighteen days old embryos were vaccinated via in ovo or day of age chickens were vaccinated via subcutaneous and challenged at 4 weeks of age with Texas GB via IM injection according to 9 CFR (Study of file with CVB).
Marek’s Disease Protection
ULTIFEND® IBD ND at minimum protective dose achieved the 9 CFR requirement of at least 80% protection from tumor lesions caused by virulent GA Marek’s Disease virus.
Eighteen days old embryos were vaccinated via in ovo or day of age chickens were vaccinated via subcutaneous and challenged at 5 days of age with virulent Marek’s disease virus GA strain according to 9 CFR (Study on file with CVB).
Be Confident in Your BD and ND Protection
One hatchery application to help optimize your Gumboro, Newcastle and Marek’s protection and bird performance.
One hatchery application to help optimize your Gumboro, Newcastle and Marek’s protection and bird performance.
An opportunity to optimize your infectious bronchitis vaccination program by taking live Newcastle vaccine and related post vaccination reactions out of the equation.

